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GRAHF II Genomic Analysis of Enhanced Receptors to Heart Failure Therapy in African Americans A.ODUWOLE MD



2/17/2015 2/16/2020 Enrollment completed.  Study is still active for follow-up.            
Paragon Evaluate the efficacy and safety of Entresto compared to Valsartan, on morbidity and mortality in Heart Failure patients (NYHA II-IV) with preserved ejection fraction A.ONWUANYI MD



2/9/2015 2/8/2020 Enrollment completed. Currently doing follow-up on existing enrolled participants                 
SPRINT ER A randomized controlled clinical trial examining the effects of a high blood pressure treatment strategy aimed at reducing systolic blood pressure (SBP) to a lower goal than currently recommended.  P. PEMU MD S. SMITH  01/24/2012 12/00/2019 This study is active, but closed to enrollment. The current IRB approval is for data analysis and collection of data for sub studies: SPRINT (ASK) and SPRINT vs. EHR (Electronic Health Records).
ASPREE/ASPREE XT A double blinded randomized, placebo-controlled primary prevention trial. The study examines whether the benefits of a low dose of Aspirin (particularly the prevention of heart disease, stroke, certain cancers and dementia) outweigh the risks in the age group of 65 years or older. P.PEMU MD S. SMITH  01/10/2015 12/00/2019 The ASPREE study has ended. ASPREE XT is a sub study, which should continue over the next 5 years. Study activity for ASPREE XT is currently on hold, while study sponsors work to get study under one central IRB. Only participants enrolled in ASPREE, may participitate in ASPREE XT.
HIV/PAH The main objective of this study is to determine the prevalence of pulmonary arterial hypertension (PAH) among HIV-infected individuals in an underserved, urban, predominantly African-American population.  M. HENRIQUES KING MD T. TEWOLDE 3/20/2013 3/20/2020 Enrollment completed. Study active only to compile and analyze ECHO and RHC findings
Sleep Study To determine if there is an association between circadian misalignment and negative cardio-metabolic outcomes in predominately African-American shift workers. K. CLARK MD T. TEWOLDE  04/01/2015 5/27/2019 Enrollment completed                                            Composing manuscript                                           Study active only to compose and analyze data
Shift Workers Ambulatory Blood Pressure Measurement in African American Non-Standard shift workers in Atlanta metro area community samples. K. CLARK MD T.TEWOLDE 9/13/2017 11/19/2019 Actively recruiting
The Morehouse-Emory Cardiovascular (MECA) Center for Health Equity Study Partnership between investigators at Morehouse School of Medicine and Emory University investigating ethnic disparities and incorporating the role of resilience factors in improving health status among African Americans in metro Atlanta. The aim of this multi-disciplinary team is to examine the associations between personal factors (psychosocial factors, socio-economic class, healthy behaviors and health beliefs) and environmental influences (neighborhood) on health behaviors and physiologic measures.





07/01/15 6/30/2019 Actively recruiting
Impact of Technology-based Intervention for Improving Self-management Behaviors in Black Adults With Poor Cardiovascular Health: MECA Clinical Intervention Project Participants in the parent MECA study are recruited for a clinical intervention examining cardiac outcomes between participants who are randomized to received Health360x (a web-based and mobile-based application) or Health360x plus personalized health coaching.  Measures of cardiovascular health are assessed at baseline and after the 6 month intervention. P. PEMU MD ELIZABETH OLORUNDARE    07/25/17 6/30/2019 Actively recruiting, then will have no cost extension to complete the 6 months visit
All of Us All of Us Research Program is a historic, longitudinal effort to
gather data from one million or more people living in the United States to accelerate research and improve health. Through this Program, researchers will have information to better understand health and disease and speed up medical breakthroughs. By understanding individual differences in people's health, neighborhood, family and lifestyle, researchers will be able to speed up medical breakthroughs and make progress toward delivering precision medicine.
P. PEMU MD E.I. OLORUNDARE MD 6/4/2018 6/3/2023 Actively enrolling